Preparation and Control of Disinfectants in Secondary Pharmaceutical Facilities

The importance of control of disinfectants approval of incoming materials and preparation of solutions to be controlled. The effectiveness of the various disinfectants can be significantly decreased if their preparation as solutions and subsequent control is not properly performed. The issues which should be considered are: a) Correct dilution of the disinfectant b) Use of adequately controlled diluents c) Sufficient […]

Uses and Limitations of Disinfectants in Secondary Pharmaceutical Facilities

With such a wide range of available disinfectant agents it is not surprising that they have different effectiveness and are used in different locations depending on their properties. Several factors can affect the effectiveness of the agent, including a) Dilution specific concentrations are usually needed. Higher concentrations are NOT always more effective. The suppliers recommendations should be followed unless otherwise […]

Categories of Disinfectants in Secondary Pharmaceutical Facilities

Categories: A wide range of disinfectants are in use, offering a range of activities and types of use, and they may be grouped together in a number of broad classifications. These are: a) Alcohols, usually ethanol or Industrial Methylated Spirit (IMS) but also other alcohols such as Isopropyl. They may be used alone or as a solvent for other disinfectants. […]

Disinfection of Drains and Sinks in Secondary Pharmaceutical Facilities

The major source or contamination in non sterile products, particularly aqueous products such as creams, oral liquids, arises from water borne organisms (e.g. Pseudomonas aeruginosa and other potentially objectionable organisms). These organisms are found commonly in drains, wash bays and sinks and their control is of critical importance. Although the regime of cleaning and disinfection is of great importance, the […]